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Myocardial bridging of the left anterior descending coronary artery is associated with reduced myocardial perfusion reserve: a 13N-ammonia PET study.

ABSTRACT: Myocardial Bridging (MB) refers to the band of myocardium that abnormally overlies a segment of a coronary artery. This paper quantitatively evaluates the influence of MB of the left anterior descending artery (LAD) on myocardial perfusion of the entire left ventricle. We studied 131 consecutive patients who underwent hybrid rest/stress 13N-ammonia positron emission tomography (PET) and coronary computed tomography angiography (CCTA) due to suspected myocardial ischemia. Patients with previous myocardial infarction and/or significant coronary artery disease (??50% stenosis) were excluded. Myocardial perfusion measurements were compared between patients with and without LAD-MB. Additionally, we evaluated the relationship between anatomical characteristics (length and depth) of LAD-MB and myocardial perfusion measurements. 17 (13%) patients presented a single LAD-MB. Global myocardial perfusion reserve (MPR) was lower in patients with LAD-MB than in patients without LAD-MB (1.9?±?0.5 vs. 2.3?±?0.6, p?

SUBMITTER: Monroy-Gonzalez AG 

PROVIDER: S-EPMC6428791 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature

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Myocardial bridging of the left anterior descending coronary artery is associated with reduced myocardial perfusion reserve: a <sup>13</sup>N-ammonia PET study.

Monroy-Gonzalez Andrea G AG   Alexanderson-Rosas Erick E   Prakken Niek H J NHJ   Juarez-Orozco Luis E LE   Walls-Laguarda Lourdes L   Berrios-Barcenas Enrique A EA   Meave-Gonzalez Aloha A   Groot Jan C JC   Slart Riemer H J A RHJA   Tio Rene A RA  

The international journal of cardiovascular imaging 20180928 2

Myocardial Bridging (MB) refers to the band of myocardium that abnormally overlies a segment of a coronary artery. This paper quantitatively evaluates the influence of MB of the left anterior descending artery (LAD) on myocardial perfusion of the entire left ventricle. We studied 131 consecutive patients who underwent hybrid rest/stress <sup>13</sup>N-ammonia positron emission tomography (PET) and coronary computed tomography angiography (CCTA) due to suspected myocardial ischemia. Patients with  ...[more]

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