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First clinical case of KPC-3-producing Klebsiella michiganensis in Europe.


ABSTRACT: Klebsiella michiganensis is a newly emerging human pathogen. We describe a case of bloodstream infection in an immunocompromised patient. The pathogen was repeatedly isolated from blood and one rectal swab, and was identified using routine standard procedures. Further investigations revealed that the K. michiganensis was multidrug resistant, carrying a plasmid harbouring a Klebsiella pneumoniae carbapenemase (KPC)-3 carbapenemase gene. This plasmid has been frequently encountered in K. pneumoniae isolates in Europe but has never been described in K. michiganensis.

SUBMITTER: Seiffert SN 

PROVIDER: S-EPMC6428935 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature

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First clinical case of KPC-3-producing <i>Klebsiella michiganensis</i> in Europe.

Seiffert S N SN   Wüthrich D D   Gerth Y Y   Egli A A   Kohler P P   Nolte O O  

New microbes and new infections 20190223


<i>Klebsiella michiganensis</i> is a newly emerging human pathogen. We describe a case of bloodstream infection in an immunocompromised patient. The pathogen was repeatedly isolated from blood and one rectal swab, and was identified using routine standard procedures. Further investigations revealed that the <i>K. michiganensis</i> was multidrug resistant, carrying a plasmid harbouring a <i>Klebsiella pneumoniae</i> carbapenemase (KPC)-3 carbapenemase gene. This plasmid has been frequently encoun  ...[more]

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