Dataset Information
Electrochemical fluoromethylation triggered lactonizations of alkenes under semi-aqueous conditions.
Ontology highlight
ABSTRACT:
SUBMITTER: Zhang S
PROVIDER: S-EPMC6429606 | biostudies-literature | 2019 Mar
REPOSITORIES: biostudies-literature
Publications
Electrochemical fluoromethylation triggered lactonizations of alkenes under semi-aqueous conditions.
Chemical science 20190214 11
An electrochemical difluoromethylation triggered lactonization of alkenes was developed for the first time. This protocol employs readily prepared CF<sub>2</sub>HSO<sub>2</sub>Na as the difluoromethylating reagent, affording unprecedented CF<sub>2</sub>H-containing lactones in moderate yields. Moreover, with CF<sub>3</sub>SO<sub>2</sub>Na as the trifluoromethylating reagent, a wide array of CF<sub>3</sub>-containing lactones were obtained under additional supporting electrolyte- and catalyst-fre ...[more]