Genetic dissection of interspecific differences in yeast thermotolerance.
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ABSTRACT:
SUBMITTER: Weiss CV
PROVIDER: S-EPMC6430122 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
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Genetic dissection of interspecific differences in yeast thermotolerance.
Weiss Carly V CV Roop Jeremy I JI Hackley Rylee K RK Chuong Julie N JN Grigoriev Igor V IV Arkin Adam P AP Skerker Jeffrey M JM Brem Rachel B RB
Nature genetics 20181008 11
Some of the most unique and compelling survival strategies in the natural world are fixed in isolated species<sup>1</sup>. To date, molecular insight into these ancient adaptations has been limited, as classic experimental genetics has focused on interfertile individuals in populations<sup>2</sup>. Here we use a new mapping approach, which screens mutants in a sterile interspecific hybrid, to identify eight housekeeping genes that underlie the growth advantage of Saccharomyces cerevisiae over it ...[more]
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