Unknown

Dataset Information

0

Plasma citrulline, arginine, nitric oxide, and blood ammonia levels in neonatal calves with acute diarrhea.


ABSTRACT: BACKGROUND:Plasma citrulline (CIT) concentration is considered to be a reliable marker of functional enterocyte mass, primarily in humans. However, information about CIT levels along with related metabolites, arginine (ARG), nitric oxide (NO), and ammonia in neonatal calves are lacking. OBJECTIVES:To compare plasma CIT, ARG, NO, and whole blood ammonia concentrations in neonatal calves with acute diarrhea with those in healthy calves and to assess their possible relationships with diarrhea-related criteria. ANIMALS:Seventy neonatal calves (60 with acute diarrhea and 10 healthy). METHODS:Observational case-control study. Diarrheic calves were classified into subgroups on the basis of etiology, severity of diarrhea, degree of dehydration, and systemic inflammatory response syndrome (SIRS) status. Plasma CIT and ARG concentrations were measured by liquid chromatography/tandem mass spectrometry. RESULTS:Plasma CIT (median [range]: 67.5 [61.9-75.4] vs 30.1 [15.0-56.1] ?mol/L) and ARG (170.7 [148.5-219.5] vs 106.1 [54.4-190.7] ?mol/L) were lower and plasma NO (4.42 [3.29-5.58] vs 6.78 [5.29-8.92] ?M) and blood ammonia concentrations (28.7 [26.1-36.9] vs 59.8 [34.6-99.5] ?mol/L) were higher in the neonatal calves with diarrhea (P?

SUBMITTER: Gultekin M 

PROVIDER: S-EPMC6430905 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature

altmetric image

Publications

Plasma citrulline, arginine, nitric oxide, and blood ammonia levels in neonatal calves with acute diarrhea.

Gultekin Mehmet M   Voyvoda Huseyin H   Ural Kerem K   Erdogan Hasan H   Balikci Canberk C   Gultekin Gamze G  

Journal of veterinary internal medicine 20190220 2


<h4>Background</h4>Plasma citrulline (CIT) concentration is considered to be a reliable marker of functional enterocyte mass, primarily in humans. However, information about CIT levels along with related metabolites, arginine (ARG), nitric oxide (NO), and ammonia in neonatal calves are lacking.<h4>Objectives</h4>To compare plasma CIT, ARG, NO, and whole blood ammonia concentrations in neonatal calves with acute diarrhea with those in healthy calves and to assess their possible relationships with  ...[more]

Similar Datasets

| S-EPMC8374159 | biostudies-literature
| S-EPMC7783447 | biostudies-literature
| S-EPMC2291275 | biostudies-literature
| S-EPMC6415715 | biostudies-literature
| S-EPMC4818739 | biostudies-literature
| S-EPMC4895490 | biostudies-literature
| S-EPMC5553148 | biostudies-other
| S-EPMC6975256 | biostudies-literature
| S-EPMC2903302 | biostudies-literature
| S-EPMC1219836 | biostudies-other