Ontology highlight
ABSTRACT:
SUBMITTER: Bothe W
PROVIDER: S-EPMC6431277 | biostudies-literature | 2019 Apr
REPOSITORIES: biostudies-literature
Bothe Wolfgang W Timek Tomasz A TA Tibayan Frederick A FA Walther Mario M Daughters George T GT Ingels Neil B NB Miller D Craig DC
The Journal of thoracic and cardiovascular surgery 20181010 4
<h4>Objective</h4>Papillary muscle (PM) displacement contributes to ischemic/functional mitral regurgitation (IMR/FMR). The displaced PMs pull the mitral leaflets into the left ventricle (ie, toward the apex) thus hampering leaflet coaptation. Intuitively apical leaflet tethering results from apical PM displacement. The 3-dimensional directions of PM displacement are, however, incompletely characterized.<h4>Methods</h4>Data from in vivo ovine models of IMR (6-8 weeks of posterolateral infarction ...[more]