The Genetic Basis of Metabolic Disease.
Ontology highlight
ABSTRACT:
SUBMITTER: Barroso I
PROVIDER: S-EPMC6432945 | biostudies-literature | 2019 Mar
REPOSITORIES: biostudies-literature
Publications
Recent developments in genetics and genomics are providing a detailed and systematic characterization of the genetic underpinnings of common metabolic diseases and traits, highlighting the inherent complexity within systems for homeostatic control and the many ways in which that control can fail. The genetic architecture underlying these common metabolic phenotypes is complex, with each trait influenced by hundreds of loci spanning a range of allele frequencies and effect sizes. Here, we review ...[more]
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2018-09-15 | GSE115725 | GEO