Ontology highlight
ABSTRACT:
SUBMITTER: Krezdorn N
PROVIDER: S-EPMC6433509 | biostudies-literature | 2019 Apr
REPOSITORIES: biostudies-literature
Krezdorn Nicco N Lian Christine G CG Wells Michael M Wo Luccie L Tasigiorgos Sotirios S Xu Shuyun S Borges Thiago J TJ Frierson Rayven M RM Stanek Ewelina E Riella Leonardo V LV Pomahac Bohdan B Murphy George F GF
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20181110 4
Face vascularized composite allografts (FVCAs) have helped patients with severe facial disfigurement, with acute rejection now largely controlled through iatrogenic immunosuppression. However, little is known regarding the incidence and mechanism(s) of more long-term pathologic alterations in FVCAs that may affect function and graft durability. Protocol surveillance biopsy specimens for up to an 8-year interval in 7 patients who received FVCAs at our institution revealed histopathologic evidence ...[more]