Ontology highlight
ABSTRACT:
SUBMITTER: Drilon A
PROVIDER: S-EPMC6434708 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Drilon Alexander A Lin Jessica J JJ Filleron Thomas T Ni Ai A Milia Julie J Bergagnini Isabella I Hatzoglou Vaios V Velcheti Vamsidhar V Offin Michael M Li Bob B Carbone David P DP Besse Benjamin B Mok Tony T Awad Mark M MM Wolf Jurgen J Owen Dwight D Camidge D Ross DR Riely Gregory J GJ Peled Nir N Kris Mark G MG Mazieres Julien J Gainor Justin F JF Gautschi Oliver O
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20180711 10
<h4>Introduction</h4>In ret proto-oncogene (RET)-rearranged lung cancers, data on the frequency of brain metastases and, in particular, the outcomes of multikinase inhibitor therapy in patients with intracranial disease are not well characterized.<h4>Methods</h4>A global, multi-institutional registry (cohort A, n = 114) and a bi-institutional data set (cohort B, n = 71) of RET-rearranged lung cancer patients were analyzed. Patients were eligible if they had stage IV lung cancers harboring a RET ...[more]