Expression of Syk and MAP4 proteins in ovarian cancer.
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ABSTRACT:
SUBMITTER: Zhang S
PROVIDER: S-EPMC6435630 | biostudies-literature | 2019 Apr
REPOSITORIES: biostudies-literature
Publications
Expression of Syk and MAP4 proteins in ovarian cancer.
Zhang Siwei S Deen Suha S Storr Sarah J SJ Yao Anqi A Martin Stewart G SG
Journal of cancer research and clinical oncology 20190208 4
<h4>Purpose</h4>We have previously reported on the prognostic importance of the calpain family of proteins in ovarian cancer, especially calpain-2. Spleen tyrosine kinase (Syk) phosphorylates a variety of cytoskeletal proteins with studies suggesting potential interactions between Syk and conventional calpains. Microtubule-associated protein 4 (MAP4) has been reported to be regulated by Syk.<h4>Methods</h4>The current study assessed Syk and MAP4 protein expression, by immunohistochemistry on a t ...[more]
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