Ontology highlight
ABSTRACT:
SUBMITTER: Hashimoto S
PROVIDER: S-EPMC6435665 | biostudies-literature | 2019 Mar
REPOSITORIES: biostudies-literature
Hashimoto Shu S Yamanaka Masaya M Yamochi Takayuki T Iwata Hisataka H Kawahara-Miki Ryouka R Inoue Masayasu M Morimoto Yoshiharu Y
Scientific reports 20190326 1
Although in vitro maturation (IVM) of oocytes is important for assisted reproduction, the rate of development of embryos from IVM oocytes is lower than from their in vivo counterparts. It has been shown that an artificial increase of intracellular cAMP before culture significantly improves oocyte developmental competence in cattle and mice. Here, we revealed that forskolin and 3-isobutyl-1-methylxanthine treatment of prophase-stage oocytes induced the expression of genes required for glycolysis, ...[more]