Ontology highlight
ABSTRACT:
SUBMITTER: Nachtergaele S
PROVIDER: S-EPMC6436393 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
Nachtergaele Sigrid S He Chuan C
Annual review of genetics 20180919
Investigations over the past eight years of chemical modifications on messenger RNA (mRNA) have revealed a new level of posttranscriptional gene regulation in eukaryotes. Rapid progress in our understanding of these modifications, particularly, N<sup>6</sup>-methyladenosine (m<sup>6</sup>A), has revealed their roles throughout the life cycle of an mRNA transcript. m<sup>6</sup>A methylation provides a rapid mechanism for coordinated transcriptome processing and turnover that is important in embr ...[more]