Unknown

Dataset Information

0

Targeted therapy in cervical cancer.


ABSTRACT: Cervical cancer continues to be a common cancer in women worldwide, especially in less developed regions where advanced stage presentations are common. Addition of bevacizumab to cytotoxic chemotherapy has been the only notable recent advance in the treatment of recurrent and metastatic cervical cancer. Outcomes in patients with locally advanced disease have also plateaued after meaningful gains were achieved with concomitant chemoradiation treatment. Recently, progress has been made in understanding the molecular aberrations in cervical cancer and new therapeutic modalities are emerging, including immune checkpoint inhibitors, therapeutic vaccines, antibody-drug conjugates, and others. In this review we will discuss the data and potential utility of these approaches.

SUBMITTER: Vora C 

PROVIDER: S-EPMC6438352 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature

altmetric image

Publications

Targeted therapy in cervical cancer.

Vora Chakor C   Gupta Sudeep S  

ESMO open 20180101 Suppl 1


Cervical cancer continues to be a common cancer in women worldwide, especially in less developed regions where advanced stage presentations are common. Addition of bevacizumab to cytotoxic chemotherapy has been the only notable recent advance in the treatment of recurrent and metastatic cervical cancer. Outcomes in patients with locally advanced disease have also plateaued after meaningful gains were achieved with concomitant chemoradiation treatment. Recently, progress has been made in understa  ...[more]

Similar Datasets

| S-EPMC4102744 | biostudies-literature
| S-EPMC10531664 | biostudies-literature
| S-EPMC6037027 | biostudies-literature
| S-EPMC8189418 | biostudies-literature
| S-EPMC7281413 | biostudies-literature
| S-EPMC8268251 | biostudies-literature
| S-EPMC3125999 | biostudies-other
| S-EPMC5065582 | biostudies-other
| S-EPMC6633885 | biostudies-literature
| S-EPMC8186785 | biostudies-literature