Ontology highlight
ABSTRACT:
SUBMITTER: Xiao Q
PROVIDER: S-EPMC6439341 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Xiao Qiaoqiao Q Guo Deyin D Chen Shuliang S
Frontiers in cellular and infection microbiology 20190322
Despite the fact that great efforts have been made in the prevention and therapy of HIV-1 infection, HIV-1/AIDS remains a major threat to global human health. Highly active antiretroviral therapy (HAART) can suppress virus replication, but it cannot eradicate latent viral reservoirs in HIV-1/AIDS patients. Recently, the clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated nuclease 9 (Cas9) system has been engineered as an effective gene-editing technology with the ...[more]