Ontology highlight
ABSTRACT:
SUBMITTER: Cho SH
PROVIDER: S-EPMC6439472 | biostudies-literature | 2018 Dec
REPOSITORIES: biostudies-literature
Cho Soo Hyun SH Shin Jeong-Hyeon JH Jang Hyemin H Park Seongbeom S Kim Hee Jin HJ Kim Si Eun SE Kim Seung Joo SJ Kim Yeshin Y Lee Jin San JS Na Duk L DL Lockhart Samuel N SN Rabinovici Gil D GD Seong Joon-Kyung JK Seo Sang Won SW
European journal of nuclear medicine and molecular imaging 20180706 13
<h4>Purpose</h4>We estimated whether amyloid involvement in subcortical regions may predict cognitive impairment, and established an amyloid staging scheme based on degree of subcortical amyloid involvement.<h4>Methods</h4>Data from 240 cognitively normal older individuals, 393 participants with mild cognitive impairment, and 126 participants with Alzheimer disease were acquired at Alzheimer's Disease Neuroimaging Initiative sites. To assess subcortical involvement, we analyzed amyloid depositio ...[more]