Ontology highlight
ABSTRACT:
SUBMITTER: Bosch A
PROVIDER: S-EPMC6440009 | biostudies-literature | 2019 Mar
REPOSITORIES: biostudies-literature
Bosch Agnes A Ott Christian C Jung Susanne S Striepe Kristina K Karg Marina V MV Kannenkeril Dennis D Dienemann Thomas T Schmieder Roland E RE
Cardiovascular diabetology 20190329 1
<h4>Background</h4>Empagliflozin has been shown to reduce cardiovascular mortality, but the underlying pathogenetic mechanisms are poorly understood. It was previously demonstrated that empagliflozin improved arterial stiffness.<h4>Methods</h4>Our analysis comprising 58 patients with type 2 diabetes mellitus identifies factors triggering the improvement of arterial stiffness. All patients participated in an investigator-initiated, prospective, double-blind, randomized, placebo-controlled, interv ...[more]