Ontology highlight
ABSTRACT:
SUBMITTER: Melnikova L
PROVIDER: S-EPMC6441048 | biostudies-literature | 2019 Mar
REPOSITORIES: biostudies-literature
Melnikova Larisa L Elizar'ev Pavel P Erokhin Maksim M Molodina Varvara V Chetverina Darya D Kostyuchenko Margarita M Georgiev Pavel P Golovnin Anton A
Scientific reports 20190329 1
Suppressor of Hairy-wing [Su(Hw)] is a DNA-binding architectural protein that participates in the organization of insulators and repression of promoters in Drosophila. This protein contains acidic regions at both ends and a central cluster of 12 zinc finger domains, some of which are involved in the specific recognition of the binding site. One of the well-described in vivo function of Su(Hw) is the repression of transcription of neuronal genes in oocytes. Here, we have found that the same Su(Hw ...[more]