Ontology highlight
ABSTRACT:
SUBMITTER: Sainz de Aja J
PROVIDER: S-EPMC6443201 | biostudies-literature | 2019 Apr
REPOSITORIES: biostudies-literature
Sainz de Aja Julio J Menchero Sergio S Rollan Isabel I Barral Antonio A Tiana Maria M Jawaid Wajid W Cossio Itziar I Alvarez Alba A Carreño-Tarragona Gonzalo G Badia-Careaga Claudio C Nichols Jennifer J Göttgens Berthold B Isern Joan J Manzanares Miguel M
The EMBO journal 20190227 7
Progenitors of the first hematopoietic cells in the mouse arise in the early embryo from <i>Brachyury</i>-positive multipotent cells in the posterior-proximal region of the epiblast, but the mechanisms that specify primitive blood cells are still largely unknown. Pluripotency factors maintain uncommitted cells of the blastocyst and embryonic stem cells in the pluripotent state. However, little is known about the role played by these factors during later development, despite being expressed in th ...[more]