Ontology highlight
ABSTRACT:
SUBMITTER: Kovatcheva-Datchary P
PROVIDER: S-EPMC6444000 | biostudies-literature | 2019 Mar
REPOSITORIES: biostudies-literature
Cell reports 20190301 13
The gut microbiota can modulate human metabolism through interactions with macronutrients. However, microbiota-diet-host interactions are difficult to study because bacteria interact in complex food webs in concert with the host, and many of the bacteria are not yet characterized. To reduce the complexity, we colonize mice with a simplified intestinal microbiota (SIM) composed of ten sequenced strains isolated from the human gut with complementing pathways to metabolize dietary fibers. We feed t ...[more]