Ontology highlight
ABSTRACT:
SUBMITTER: Vasilovici AF
PROVIDER: S-EPMC6444280 | biostudies-literature | 2019 May
REPOSITORIES: biostudies-literature
Vasilovici Alina F AF Grigore Lavinia Elena LE Ungureanu Loredana L Fechete Oana O Candrea Elisabeta E Trifa Adrian P AP Vișan Simona S Șenilă Simona S Cosgarea Rodica R
Oncology letters 20181119 5
Melanoma represents the most aggressive skin cancer, with an unpredictable and often treatment resistant behavior. The etiology of melanoma is multifactorial and includes both environmental and genetic factors. Recent evidence indicates that vitamin D has a role in the development and progression of melanoma. The biologically active form of vitamin D/1,25-dihydroxyvitamin D3 acts by binding to a intranuclear receptor; vitamin D receptor (VDR). Single nucleotide polymorphisms (SNPs) in the vitami ...[more]