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A diastereoselective approach to axially chiral biaryls via electrochemically enabled cyclization cascade.

ABSTRACT: A diastereoselective approach to axially chiral imidazopyridine-containing biaryls has been developed. The reactions proceed through a radical cyclization cascade to construct the biaryls with good to excellent central-to-axial chirality transfer.

SUBMITTER: Yan H

PROVIDER: S-EPMC6444422 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature

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A diastereoselective approach to axially chiral biaryls via electrochemically enabled cyclization cascade.

Yan Hong H Mao Zhong-Yi ZY Hou Zhong-Wei ZW Song Jinshuai J Xu Hai-Chao HC

Beilstein journal of organic chemistry 20190328

A diastereoselective approach to axially chiral imidazopyridine-containing biaryls has been developed. The reactions proceed through a radical cyclization cascade to construct the biaryls with good to excellent central-to-axial chirality transfer. ...[more]

PMID: 30992728

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