Key metabolic parameters change significantly in early breast cancer survivors: an explorative PILOT study.

ABSTRACT: BACKGROUND:With increasing number of breast cancer survivors, more attention is drawn to long-term consequences of curative cancer treatment. Adjuvant treatment of breast cancer patients is associated with several unfavorable medical conditions, including dyslipidemia, insulin resistance, and obesity, potentially leading to cardiovascular disease and/or the metabolic syndrome. The aim of this explorative study is to investigate metabolic side effects of adjuvant treatment in breast cancer patients. METHODS:A cohort of 13 premenopausal and 20 postmenopausal women with early stage breast cancer were extensively examined prior to, immediately after and 1 year after ended adjuvant chemotherapy and compared with healthy controls (N = 36) matched by age and menopausal status. Repeated examinatio

SUBMITTER: Fredslund SO 

PROVIDER: S-EPMC6444586 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature