Ontology highlight
ABSTRACT:
SUBMITTER: Coronel-Hernandez J
PROVIDER: S-EPMC6444875 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Coronel-Hernández Jossimar J López-Urrutia Eduardo E Contreras-Romero Carlos C Delgado-Waldo Izamary I Figueroa-González Gabriela G Campos-Parra Alma D AD Salgado-García Rebeca R Martínez-Gutierrez Antonio A Rodríguez-Morales Miguel M Jacobo-Herrera Nadia N Terrazas Luis Ignacio LI Silva-Carmona Abraham A López-Camarillo César C Pérez-Plasencia Carlos C
Cancer cell international 20190402
<h4>Background</h4>Invasion and metastasis are determinant events in the prognosis of Colorectal cancer (CRC), a common neoplasm worldwide. An important factor for metastasis is the acquired capacity of the cell to proliferate and invade adjacent tissues. In this paper, we explored the role of micro-RNA-26a in the regulation of proliferation and migration in CRC-derived cells through the negative regulation of PTEN, a key negative regulator of the AKT pathway.<h4>Methods</h4>Expression levels of ...[more]