Ontology highlight
ABSTRACT:
SUBMITTER: Hadjipanayis CG
PROVIDER: S-EPMC6445645 | biostudies-literature | 2019 Feb
REPOSITORIES: biostudies-literature
Journal of neuro-oncology 20190114 3
The US Food and Drug Administration (FDA) approved 5-aminolevulinic acid (5-ALA; Gleolan<sup>®</sup>; photonamic GmbH and Co. KG) for use as an intraoperative optical imaging agent in patients with suspected high-grade gliomas (HGGs) in 2017. This was the first ever optical imaging agent approved as an adjunct for the visualization of malignant tissue during surgery for brain tumors. The approval occurred a decade after European approval and a multicenter, phase III randomized trial which confir ...[more]