Red-emitting pyrene-benzothiazolium: unexpected selectivity to lysosomes for real-time cell imaging without alkalinizing effect.
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ABSTRACT:
SUBMITTER: Abeywickrama CS
PROVIDER: S-EPMC6446231 | biostudies-literature | 2019 Mar
REPOSITORIES: biostudies-literature
Publications
Red-emitting pyrene-benzothiazolium: unexpected selectivity to lysosomes for real-time cell imaging without alkalinizing effect.
Abeywickrama Chathura S CS Wijesinghe Kaveesha J KJ Stahelin Robert V RV Pang Yi Y
Chemical communications (Cambridge, England) 20190301 24
A series of pyrene-benzothiazolium probes were synthesized. By replacing the pyridinium with a benzothiazolium unit, the selectivity of pyrene-derivatives is found to switch from nuclear to cellular lysosomes. New probes do not require proton participation and exhibit high biocompatibility and long-term imaging ability. ...[more]
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