Epstein-Barr virus strain variation and cancer.
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ABSTRACT:
SUBMITTER: Kanda T
PROVIDER: S-EPMC6447851 | biostudies-literature | 2019 Apr
REPOSITORIES: biostudies-literature
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Epstein-Barr virus strain variation and cancer.
Kanda Teru T Yajima Misako M Ikuta Kazufumi K
Cancer science 20190221 4
Epstein-Barr virus (EBV) is a human tumor virus and is etiologically linked to various malignancies. Certain EBV-associated diseases, such as Burkitt lymphomas and nasopharyngeal carcinomas, are endemic and exhibit biased geographic distribution worldwide. Recent advances in deep sequencing technology enabled high-throughput sequencing of the EBV genome from clinical samples. Rapid cloning and sequencing of cancer-derived EBV genomes, followed by reconstitution of infectious virus, have also bec ...[more]
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