Ontology highlight
ABSTRACT:
SUBMITTER: Zhang Y
PROVIDER: S-EPMC6448837 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Zhang Yang Y Chen Jiannan J Wang Yu Y Wang Dehua D Cong Weihui W Lai Bo Shiun BS Zhao Yi Y
PloS one 20190404 4
MiRNAs and proteins play important roles in different stages of breast tumor development and serve as biomarkers for the early diagnosis of breast cancer. A new algorithm that combines machine learning algorithms and multilayer complex network analysis is hereby proposed to explore the potential diagnostic values of miRNAs and proteins. XGBoost and random forest algorithms were employed to screen the most important miRNAs and proteins. Maximal information coefficient was applied to assess intral ...[more]