A pilot study of GABAB correlates with resting-state functional connectivity in five depressed female adolescents.
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ABSTRACT:
SUBMITTER: Balzekas I
PROVIDER: S-EPMC6449039 | biostudies-literature | 2018 Sep
REPOSITORIES: biostudies-literature
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A pilot study of GABA<sub>B</sub> correlates with resting-state functional connectivity in five depressed female adolescents.
Balzekas Irena I Lewis Charles P CP Shekunov Julia J Port John D JD Worrell Gregory A GA Joon Jo Hang H Croarkin Paul E PE
Psychiatry research. Neuroimaging 20180531
Connectivity features based on resting-state (RS) functional magnetic resonance imaging (fMRI) demonstrate great promise as biomarkers to guide diagnosis and treatment in major depressive disorder (MDD). However, there is a pressing need for valid, reliable biomarkers closer to the bedside for clinical research and practice. This study directly compared RS-fMRI connectivity features with transcranial magnetic stimulation (TMS) neurophysiological measures, long interval cortical inhibition (LICI) ...[more]
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