Ontology highlight
ABSTRACT:
SUBMITTER: Hernandez-Preciado MR
PROVIDER: S-EPMC6450450 | biostudies-literature | 2019 Mar
REPOSITORIES: biostudies-literature
Hernández-Preciado Martha Rocio MR Morán-Moguel María Cristina MC Dávalos-Rodríguez Ingrid Patricia IP Enríquez-Barajas Christian Michel CM Valdovinos-Maravilla Juan Paulo JP Díaz-Pérez Ana Lilia AL Silva-Castro Daniel Efraín DE González-López Laura L Gámez-Nava Jorge Ivan JI Aceves-Aceves Mario Alberto MA Salazar-Páramo Mario M
Genetic testing and molecular biomarkers 20190213 3
<h4>Aim</h4>The present study looked for variation in the miRNA-24 sequence, and evaluated the associations between the dihydrofolate reductase (DHFR) gene-829 C-T polymorphism and plasma DHFR concentrations with response to methotrexate (MTX) treatment in Mexican patients with rheumatoid arthritis (RA).<h4>Methods</h4>A total of 135 women with RA were classified as responders (disease activity score [DAS28] <3.2) or nonresponders to MTX (DAS28 > 3.2). We determined the genotype of the patients ...[more]