Ontology highlight
ABSTRACT:
SUBMITTER: Saldin LT
PROVIDER: S-EPMC6450457 | biostudies-literature | 2019 Mar
REPOSITORIES: biostudies-literature
Tissue engineering. Part A 20190301 5-6
<h4>Impact statement</h4>Extracellular matrix (ECM) biomaterials were used to treat esophageal cancer patients after cancer resection and promoted regrowth of normal mucosa without recurrence of cancer. The present study investigates the mechanisms by which these materials were successful to prevent the cancerous phenotype. ECM downregulated neoplastic esophageal cell function (proliferation, metabolism), but normal esophageal epithelial cells were unaffected <i>in vitro</i>, and suggests a mole ...[more]