Crystallization of the human tetraspanin protein CD9.
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ABSTRACT:
SUBMITTER: Umeda R
PROVIDER: S-EPMC6450527 | biostudies-literature | 2019 Apr
REPOSITORIES: biostudies-literature
Publications
Crystallization of the human tetraspanin protein CD9.
Umeda Rie R Nishizawa Tomohiro T Nureki Osamu O
Acta crystallographica. Section F, Structural biology communications 20190402 Pt 4
The tetraspanin family of proteins with four membrane-spanning proteins function in a wide range of physiological processes in higher organisms, including cell migration and proliferation, cell fusion, fertilization and virus infection. Although the recently reported structure of CD81 unveiled the basic architecture of this family for the first time, further structural and functional studies are required in order to understand the mechanistic details of the complicated functions of the tetraspan ...[more]
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