Basal cortisol, cortisol reactivity, and telomere length: A systematic review and meta-analysis.

ABSTRACT: The objective of the present study is to synthesize the existing empirical literature and perform a meta-analysis of published data on the relationship between cortisol and telomere length. We systematically searched studies that examined the relationship between cortisol and telomere length in humans on electronic databases and screened reference sections of included articles. Fourteen studies were included in the meta-analysis, with effect sizes being extracted for two cortisol measures: basal cortisol levels and cortisol reactivity to acute psychological stress. Results from random effects models showed that basal cortisol levels (13 effect sizes from 12 cross-sectional studies, N = 3675 participants) were not significantly correlated with telomere length (r =-0.05, 95% CI [-0.11, 0.02]

SUBMITTER: Jiang Y 

PROVIDER: S-EPMC6450740 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature