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Appearance of myocardial fibrosis during long-term follow up in a patient with apical hypertrophy.


ABSTRACT: A 67-year-old man without symptoms presented with significant negative T wave on electrocardiography. No significant abnormality was detected by echocardiography. Cardiac magnetic resonance imaging (CMR) showed trivial hypertrophied myocardium in apex. During follow up of 9 years, serial CMR scans revealed the appearance and expansion of late gadolinium enhancement in apex. The patient had never complained of cardiac symptoms such as chest pain, palpitation, or syncope during follow up. We experienced the appearance of significant myocardial fibrosis in a patient with apical hypertrophy. <Learning objective: Apical hypertrophy is characterized by hypertrophied apex and giant negative T wave. From this report, we appreciate the importance of serial cardiac magnetic resonance imaging to follow the progress of hypertrophied myocardium even for patients without significant gadolinium enhancement who can be in a premonitory state of irreversible fibrosis.>.

SUBMITTER: Nakao R 

PROVIDER: S-EPMC6451050 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature

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Appearance of myocardial fibrosis during long-term follow up in a patient with apical hypertrophy.

Nakao Risako R   Fukushima Kenji K   Nagao Michinobu M   Hagiwara Nobuhisa N  

Journal of cardiology cases 20181221 4


A 67-year-old man without symptoms presented with significant negative T wave on electrocardiography. No significant abnormality was detected by echocardiography. Cardiac magnetic resonance imaging (CMR) showed trivial hypertrophied myocardium in apex. During follow up of 9 years, serial CMR scans revealed the appearance and expansion of late gadolinium enhancement in apex. The patient had never complained of cardiac symptoms such as chest pain, palpitation, or syncope during follow up. We exper  ...[more]

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