Ontology highlight
ABSTRACT:
SUBMITTER: Golub M
PROVIDER: S-EPMC6451406 | biostudies-literature | 2019 Mar
REPOSITORIES: biostudies-literature
Golub Maksym M Guillon Virginia V Gotthard Guillaume G Zeller Dominik D Martinez Nicolas N Seydel Tilo T Koza Michael M MM Lafaye Céline C Clavel Damien D von Stetten David D Royant Antoine A Peters Judith J
Journal of the Royal Society, Interface 20190301 152
Cyan fluorescent proteins (CFPs) are variants of green fluorescent proteins in which the central tyrosine of the chromophore has been replaced by a tryptophan. The increased bulk of the chromophore within a compact protein and the change in the positioning of atoms capable of hydrogen bonding have made it difficult to optimize their fluorescence properties, which took approximately 15 years between the availability of the first useable CFP, enhanced cyan fluorescent protein (ECFP), and that of a ...[more]