Structural Biology: Piezo Senses Tension through Curvature.

ABSTRACT: The sensations of sound, touch and pressure are mediated by mechanotransduction channels - transmembrane proteins whose ionic permeabilities are gated by mechanical forces. New structures of Piezo1 by cryoEM lead to the suggestion that this channel might sense membrane tension through changes in the local curvature of the membrane.

SUBMITTER: Liang X 

PROVIDER: S-EPMC6452451 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature