Ontology highlight
ABSTRACT:
SUBMITTER: Chakravarty J
PROVIDER: S-EPMC6453476 | biostudies-literature | 2019 Mar
REPOSITORIES: biostudies-literature
Chakravarty Jaya J Hasker Epco E Kansal Sangeeta S Singh Om Prakash OP Malaviya Paritosh P Singh Abhishek Kumar AK Chourasia Ankita A Singh Toolika T Sudarshan Medhavi M Singh Akhil Pratap AP Singh Bhawana B Singh Rudra Pratap RP Ostyn Bart B Fakiola Michaela M Picado Albert A Menten Joris J Blackwell Jenefer M JM Wilson Mary E ME Sacks David D Boelaert Marleen M Sundar Shyam S
PLoS neglected tropical diseases 20190327 3
<h4>Background</h4>Asymptomatic Leishmania donovani infections outnumber clinical presentations, however the predictors for development of active disease are not well known. We aimed to identify serological, immunological and genetic markers for progression from L. donovani infection to clinical Visceral Leishmaniasis (VL).<h4>Methods</h4>We enrolled all residents >2 years of age in 27 VL endemic villages in Bihar (India). Blood samples collected on filter paper on two occasions 6-12 months apar ...[more]