Ontology highlight
ABSTRACT:
SUBMITTER: Kim S
PROVIDER: S-EPMC6453716 | biostudies-literature | 2018 Dec
REPOSITORIES: biostudies-literature
Kim Soyon S Cui Zhong-Kai ZK Koo Bonhye B Zheng Jiwen J Aghaloo Tara T Lee Min M
ACS applied materials & interfaces 20181121 48
Tuning hydrogel degradation enables effective and successful tissue regeneration by modulating cellular behaviors and matrix formation. In this work, we develop a novel degradable hydrogel scaffold on the basis of a unique enzyme-substrate complex by photocrosslinking. Chitosan and lysozyme are chemically modified with methacrylate moieties to be tethered in hydrogels, and in the presence of riboflavin initiator, these hydrogels are cured by blue light irradiation. The incorporation of lysozyme ...[more]