Ontology highlight
ABSTRACT:
SUBMITTER: Yang MY
PROVIDER: S-EPMC6454540 | biostudies-literature | 2017 May
REPOSITORIES: biostudies-literature
Yang M Y MY Cushman R A RA Fortune J E JE
Molecular human reproduction 20170501 5
<h4>Study question</h4>Does anti-Müllerian hormone (AMH) inhibit activation (initiation of growth) of primordial follicles and attenuate the growth of primary follicles in cattle, an excellent animal model for human ovarian follicular development?<h4>Summary answer</h4>AMH inhibited activation of bovine primordial follicles and attenuated the growth of activated follicles in vitro.<h4>What is known already</h4>In mice null mutant for AMH, the pool of primordial follicles is depleted prematurely ...[more]