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Anti-Mullerian hormone inhibits activation and growth of bovine ovarian follicles in vitro and is localized to growing follicles.


ABSTRACT:

SUBMITTER: Yang MY 

PROVIDER: S-EPMC6454540 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature

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Anti-Müllerian hormone inhibits activation and growth of bovine ovarian follicles in vitro and is localized to growing follicles.

Yang M Y MY   Cushman R A RA   Fortune J E JE  

Molecular human reproduction 20170501 5


<h4>Study question</h4>Does anti-Müllerian hormone (AMH) inhibit activation (initiation of growth) of primordial follicles and attenuate the growth of primary follicles in cattle, an excellent animal model for human ovarian follicular development?<h4>Summary answer</h4>AMH inhibited activation of bovine primordial follicles and attenuated the growth of activated follicles in vitro.<h4>What is known already</h4>In mice null mutant for AMH, the pool of primordial follicles is depleted prematurely  ...[more]

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