Impairment and restrictions in possibly benign multiple sclerosis.

ABSTRACT:

Objective

The aim was to describe a broad range of health dimensions in possibly benign multiple sclerosis (MS) hypothesizing that despite some limitations there is a high adaptation to the disease.

Methods

All patients from an outpatient university clinic data registry with an Expanded Disability Status Scale (EDSS) ≤3.5 and disease duration ≥15 years were addressed in a cross-sectional study. Physical impairment, neuropsychological functioning but also influence on activities and patient reported outcome measures including coping were studied.

Results

One hundred and twenty-five patients could be included (mean EDSS: 2.8; mean disease duration: 24 years). Cognitive impairment was minor (8%) but fatigue (73%) and depression (46%) were prevalent. Nevertheless, QOL and

SUBMITTER: Schaefer LM 

PROVIDER: S-EPMC6456783 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature