Ontology highlight
ABSTRACT:
SUBMITTER: Young BC
PROVIDER: S-EPMC6457891 | biostudies-literature | 2019 Feb
REPOSITORIES: biostudies-literature
Young Bernadette C BC Earle Sarah G SG Soeng Sona S Sar Poda P Kumar Varun V Hor Songly S Sar Vuthy V Bousfield Rachel R Sanderson Nicholas D ND Barker Leanne L Stoesser Nicole N Emary Katherine Rw KR Parry Christopher M CM Nickerson Emma K EK Turner Paul P Bowden Rory R Crook Derrick W DW Wyllie David H DH Day Nicholas Pj NP Wilson Daniel J DJ Moore Catrin E CE
eLife 20190222
Pyomyositis is a severe bacterial infection of skeletal muscle, commonly affecting children in tropical regions, predominantly caused by <i>Staphylococcus aureus</i>. To understand the contribution of bacterial genomic factors to pyomyositis, we conducted a genome-wide association study of <i>S. aureus</i> cultured from 101 children with pyomyositis and 417 children with asymptomatic nasal carriage attending the Angkor Hospital for Children, Cambodia. We found a strong relationship between bacte ...[more]