Ontology highlight
ABSTRACT:
SUBMITTER: Chen GY
PROVIDER: S-EPMC6457987 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
Chen Guan-Yuan GY Zhang Qibin Q
Analytical and bioanalytical chemistry 20181108 2
Oxylipins, a subclass of lipid mediators, are metabolites of various polyunsaturated fatty acids with crucial functions in regulation of systemic inflammation. Elucidation of their roles in pathological conditions requires accurate quantification of their levels in biological samples. We refined an ultra-performance liquid chromatography-multiple reaction monitoring-mass spectrometry (UPLC-MRM-MS)-based workflow for comprehensive and specific quantification of 131 endogenous oxylipins in human p ...[more]