Stage-matched survival differences by ethnicity among gastric cancer patients of Asian ancestry treated in the United States.

ABSTRACT:

Background

Differences have been noted in overall survival (OS) in gastric cancer (GC) between trials conducted in Western vs Asian countries. The National Cancer Database (NCDB) reports outcomes and patient/disease variables relevant to OS.

Methods

Using NCDB, we identified 89 558 adult patients with GC diagnosed (2004-2012), where self-reported race/ethnicity was available. Cox proportional hazard model was used to calculate multivariable hazard ratio (HR) of death, adjusting for race/ethnicity, age, gender, insurance, histology, grade, location, stage, and treatment type.

Results

After adjustment, Asian patients had improved OS (HR = 0.74, 95% confidence intervals [CI] = 0.71-0.77). There were differences in OS between Asian ethnicities compared with white patients

SUBMITTER: Rhome RM 

PROVIDER: S-EPMC6458087 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature