Identification of Long Non-coding and Messenger RNAs Differentially Expressed Between Primary and Metastatic Melanoma.
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ABSTRACT:
SUBMITTER: Sun L
PROVIDER: S-EPMC6459964 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Publications
Identification of Long Non-coding and Messenger RNAs Differentially Expressed Between Primary and Metastatic Melanoma.
Sun Ledong L Guan Zhiguang Z Wei Shanshan S Tan Rui R Li Pengfei P Yan Lu L
Frontiers in genetics 20190405
<b>Purpose:</b> Melanoma is the most aggressive and life-threatening cutaneous cancer. To explore new treatment strategies, it is essential to identify the mechanisms underlying melanoma tumorigenesis and metastasis. <b>Methods:</b> In the current study, we demonstrated altered expression of long non-coding RNA (lncRNA) and messenger RNA (mRNA) in melanoma using data from the Cancer Genome Atlas (TCGA) database. Gene Ontology (GO), Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment, and p ...[more]
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