Ontology highlight
ABSTRACT:
SUBMITTER: She Z
PROVIDER: S-EPMC6460116 | biostudies-literature | 2019 May
REPOSITORIES: biostudies-literature
She Zhun Z Geng Zhi Z Xu Jian-Hua JH Li Yan-Hua YH Dong Yu-Hui YH
Protein science : a publication of the Protein Society 20190401 5
The bacterial type VI secretion system (T6SS) utilizes many toxic effectors to gain advantage over interbacterial competition and eukaryotic host infection. Meanwhile, the cognate immunity proteins of these effectors are employed to protect themselves from the virulence. TseT and TsiT form an effector-immunity (E-I) protein pair secreted by T6SS of Pseudomonas aeruginosa. TseT is toxic for other bacteria, whereas TsiT can suppress the virulence of TseT. Here, we report the crystal structure of T ...[more]