Ontology highlight
ABSTRACT:
SUBMITTER: Cignarella F
PROVIDER: S-EPMC6460288 | biostudies-literature | 2018 Jun
REPOSITORIES: biostudies-literature
Cell metabolism 20180601 6
Multiple sclerosis (MS) is more common in western countries with diet being a potential contributing factor. Here we show that intermittent fasting (IF) ameliorated clinical course and pathology of the MS model, experimental autoimmune encephalomyelitis (EAE). IF led to increased gut bacteria richness, enrichment of the Lactobacillaceae, Bacteroidaceae, and Prevotellaceae families and enhanced antioxidative microbial metabolic pathways. IF altered T cells in the gut with a reduction of IL-17 pro ...[more]