Multimodal magnetic resonance imaging to identify stroke onset within 6 h in patients with large vessel occlusions.

ABSTRACT:

Introduction

Mechanical thrombectomy within 6 h after stroke onset improves the outcome in patients with large vessel occlusions. The aim of our study was to establish a model based on diffusion weighted and perfusion weighted imaging to provide an accurate prediction for the 6 h time-window in patients with unknown time of stroke onset.

Patients and methods

A predictive model was designed based on data from the DEFUSE 2 study and validated in a subgroup of patients with large vessel occlusions from the AXIS 2 trial.

Results

We constructed the model in 91 patients from DEFUSE 2. The following parameters were independently associated with <6 h time-window and included in the model: interquartile range and median relative diffusion weighted imaging, hypoperfusion intens

SUBMITTER: Wouters A 

PROVIDER: S-EPMC6460412 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature