Ontology highlight
ABSTRACT:
SUBMITTER: Tasa T
PROVIDER: S-EPMC6460570 | biostudies-literature | 2019 Mar
REPOSITORIES: biostudies-literature
Tasa Tõnis T Krebs Kristi K Kals Mart M Mägi Reedik R Lauschke Volker M VM Haller Toomas T Puurand Tarmo T Remm Maido M Esko Tõnu T Metspalu Andres A Vilo Jaak J Milani Lili L
European journal of human genetics : EJHG 20181112 3
Pharmacogenomics aims to tailor pharmacological treatment to each individual by considering associations between genetic polymorphisms and adverse drug effects (ADEs). With technological advances, pharmacogenomic research has evolved from candidate gene analyses to genome-wide association studies. Here, we integrate deep whole-genome sequencing (WGS) information with drug prescription and ADE data from Estonian electronic health record (EHR) databases to evaluate genome- and pharmacome-wide asso ...[more]