Dataset Information
A multi-centre interventional case series of 259 ab-interno Xen gel implants for glaucoma, with and without combined cataract surgery.
Ontology highlight
ABSTRACT: Aims
To assess the efficacy of Xen in reducing intraocular pressure (IOP) in varying glaucoma subtypes. To assess the effect of combined phacoemulsification. To determine the frequency of complications and explore further bleb management needed.Methods
Retrospective case note review of all patients undergoing Xen implantation across four centres from August 2015 to May 2017.Results
In total, 259 consecutive surgeries of 226 patients were reviewed. IOP reduced from 19.3 (SD?±?6.0) mmHg preoperatively to 14.2 (SD?±?4.4) at month 12 and 13.5 (SD?±?3.3) at month 18 (p?ConclusionsXen reduces IOP and medications at 18 months. Adverse events are uncommon. Careful postoperative surveillance and low threshold for bleb management is needed. Xen is safe and effective in mild to moderate glaucoma.
SUBMITTER: Karimi A
PROVIDER: S-EPMC6460711 | biostudies-literature | 2019 Mar
REPOSITORIES: biostudies-literature
Publications
A multi-centre interventional case series of 259 ab-interno Xen gel implants for glaucoma, with and without combined cataract surgery.
Eye (London, England) 20181024 3
<h4>Aims</h4>To assess the efficacy of Xen in reducing intraocular pressure (IOP) in varying glaucoma subtypes. To assess the effect of combined phacoemulsification. To determine the frequency of complications and explore further bleb management needed.<h4>Methods</h4>Retrospective case note review of all patients undergoing Xen implantation across four centres from August 2015 to May 2017.<h4>Results</h4>In total, 259 consecutive surgeries of 226 patients were reviewed. IOP reduced from 19.3 (S ...[more]