Untargeted metabolomic analysis in non-fasted diabetic dogs by UHPLC-HRMS.
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ABSTRACT:
SUBMITTER: O'Kell AL
PROVIDER: S-EPMC6461041 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
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Untargeted metabolomic analysis in non-fasted diabetic dogs by UHPLC-HRMS.
O'Kell A L AL Garrett T J TJ Wasserfall C C Atkinson M A MA
Metabolomics : Official journal of the Metabolomic Society 20190122 2
<h4>Introduction</h4>We recently identified variances in serum metabolomic profiles between fasted diabetic and healthy dogs, some having similarities to those identified in human type 1 diabetes.<h4>Objectives</h4>Compare untargeted metabolomic profiles in the non-fasted state.<h4>Methods</h4>Serum from non-fasted diabetic (n = 6) and healthy control (n = 6) dogs were analyzed by liquid chromatography-high resolution mass spectrometry.<h4>Results</h4>Clear clustering of metabolites between grou ...[more]
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