Label-free quantitative proteomics identifies Smarca4 is involved in vascular calcification.
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ABSTRACT:
SUBMITTER: Wang C
PROVIDER: S-EPMC6461080 | biostudies-literature | 2019 Nov
REPOSITORIES: biostudies-literature
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Label-free quantitative proteomics identifies Smarca4 is involved in vascular calcification.
Wang Chan C Tang Yun Y Wang Yanmei Y Li Guisen G Wang Li L Li Yi Y
Renal failure 20191101 1
Vascular calcification (VC) is a pathological process characterized by abnormal deposition of calcium phosphate, hydroxyapatite and other mineral substances in the vascular wall. Hyperphosphorus is an important risk factor associated with VC in the general population and patients with chronic kidney disease (CKD). However, there is still a lack of early biomarkers for hyperphosphorus induced VC. We established a calcific rat aorta vascular smooth muscle cells (RASMCs) model by stimulating with β ...[more]
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